 Clostridium Perfringens Type A
Toxoid
Beef Cattle Disease
Clostridium perfringens Type A is a strain of bacteria
that can rapidly produce harmful amounts of toxins in beef and dairy
cattle if an intestinal disruption occurs. This, in turn, can lead
to serious and often deadly gastrointestinal diseases, including
hemorrhagic bowel syndrome (HBS).
In an effort to address these emerging diseases, Novartis Animal
Health has introduced the first USDA conditionally licensed vaccine
for cattle – Clostridium Perfringens Type A Toxoid. This vaccine
aids in the control of disease syndromes caused by the alpha toxin
of C. perfringens.
Research demonstrates that C. perfringens Type A is associated
with:
-
Abomasal ulcers, abomasal hemorrhage and abdominal
tympany in calves – Beef and dairy calves show signs of quick
onset of abdominal distention with pain, bloat, depression,
feed refusal and sudden death. While there is more than one
cause, researchers have isolated C. perfringens Type A from
affected calves in several studies.
-
Hemorrhagic bowel syndrome (HBS) in mature cows – HBS
strikes apparently healthy cows without much warning, and
has an estimated fatality rate of 85 percent or higher within
the first 24-36 hours. It is more prevalent in dairy cows, but
it also has been reported in beef cattle.
The National Animal Health Monitoring System reports that the number
of operations reporting their initial cases of HBS increased dramatically
between 1996 and 2002, supporting opinions that this is an emerging
disease.
For more information, read the in-depth
report on C. perfringens Type A.
| Product
Highlights |
Aids
in the control of disease syndromes caused by the alpha toxin
of Clostridium perfringens
- C. perfringens Type A is implicated in serious
and often deadly diseases, such as hemorrhagic bowel syndrome
in mature dairy and beef cows
- C. perfringens Type A also is deadly in calves and is
commonly isolated in cases where abomasal ulcers, abomasal hemorrhage
and abdominal tympany are found |
The
first conditionally licensed C. perfringens Type
A vaccine for cattle
- Tested against a USDA standardized test
- Produced double the level of international antitoxin units required by USDA |
Field
studies demonstrate product safety
- Administration to 867 dairy and beef cattle, both open and pregnant, demonstrated
safety of product when used according to label directions |
Type
A protection that 7-way vaccines don’t have
- Standard clostridial 7-way vaccines don’t offer protection against the
alpha toxin of C. perfringens Type A and there is no cross protection
from other toxin types |
The
product should only be used in cattle
- Safe for pregnant and non-pregnant cattle |
| Contains
a proprietary dual-component adjuvant system |
How
much to give
- Administer 2 mL subcutaneously. Revaccinate in 2-4 weeks. Calves vaccinated
prior to 5 months of age should be revaccinated at 5-6 months of age. Revaccinate
annually or as recommended by your veterinarian. |
| Package
sizes: 10 and 50 doses |
|
