ReproSTAR® L5 HB
Dairy Cattle Vaccine

Product Information [pdf]

ReproSTAR® L5 HB:

• Is an inactivated vaccine that helps prevent disease caused by five strains of lepto – including Lepto hardjo-bovis, the most prevalent cause of bovine leptospirosis in U.S. cattle1

• Hardjo-bovis is the only hardjo that afflicts cattle in the United States, but very few vaccines actually contain this fraction – ReproSTAR does

• Contains an L. hardjo-bovis isolate from a U.S. dairy herd that was experiencing poor conception rates – and was diagnosed with L. hardjo-bovis

• Also aids in protection against diseases caused by L. canicola, L. grippotyphosa, L. icterohaemorrhagiae and L. pomona

• Approved for use in all cattle, including pregnant cows and heifers

L. hardjo-bovis leads to extra days open, infertility and rebreeding. It can be extremely costly for dairy producers, due to significantly lower conception rates and early embryonic death.

Diagnosis is difficult because cattle often won’t show clinical signs. Unfortunately, infected cattle can shed continuously and spread the disease within a herd, so prevention is key.

Calves can be a host when born, and infect herd mates immediately after birth. Vaccinating calves, especially replacement heifers, early with ReproSTAR L5 HB may help reduce the risk of those animals becoming lifetime carriers of L. hardjo-bovis.  

1. Zuerner RL, et al. Repetitive sequence element cloned from Leptospira interrogans serovar hardjo type hardjo-bovis provides a sensitive diagnostic probe for bovine leptospirosis. J Clin Microbiol. 1988;26:2495-2500.
2. Novartis makes no claims concerning the superiority of the U.S. isolate in ReproSTAR to the Australian isolate in Spirovac, which is a registered trademark of Pfizer, Inc.